Matrixyl (palmitoyl pentapeptide)
Matrixyl (palmitoyl pentapeptide)
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Meet your supplier
Distributor / Wholesaler • 3 yr • 
UNITED KINGDOM
56%
On-time delivery rate
≤24h
Response Time
75
Employee Size
$500K
Annual Revenue
588
Products Sold
Location
Belfast, United Kingdom
Matrixyl (Palmitoyl Pentapeptide‑4) is a trademarked cosmetic peptide developed by Sederma/Croda, designed to stimulate collagen and elastin synthesis, reduce wrinkles, and improve skin firmness. It is available in several commercial configurations such as Matrixyl®, Matrixyl® 3000, Matrixyl® Synthe’6, and Matrixyl® Morphomics®.
KEY FEATURES
Collagen stimulation: Boosts synthesis of collagen types I, III, and IV by up to 350% in vitro.
Fibronectin & elastin: Increases production by up to 200%, improving elasticity.
Wrinkle reduction: Clinical studies show visible decreases in wrinkle depth and fine lines.
Skin repair: Supports wound healing and dermal regeneration.
Non‑irritating: Gentler than retinoids, compatible with other actives.
TECHNICAL SPECIFICATIONS
INCI Name (original Matrixyl): Palmitoyl Pentapeptide‑4 (Pal‑KTTKS).
Sequence: Lys‑Thr‑Thr‑Lys‑Ser (KTTKS) with palmitoyl fatty acid chain for enhanced penetration.
Molecular Weight: ~805 Da
Form: Cosmetic grade peptide, ≥95% purity, typically supplied as powder or solution
Solubility: Water‑soluble when formulated with carriers.
Recommended Concentration: 3–5% in topical formulations (serums, creams, lotions)
Application Protocol: Twice daily; results visible after 4–8 weeks
Storage: 4–7 °C, stable for 24 months (Matrixyl 3000)
AVALAIBLE CONFIGURATION
Matrixyl® (original) — Palmitoyl Pentapeptide‑4. This was the first generation peptide, proven to stimulate collagen types I, III, and IV, reduce wrinkles, and improve skin firmness.
Matrixyl® 3000 — A blend of Palmitoyl Tripeptide‑1 and Palmitoyl Tetrapeptide‑7. It enhances collagen and elastin production while also reducing inflammation, making it one of the most widely used versions in serums.
Matrixyl® Synthe’6 — Palmitoyl Tripeptide‑38. This variant targets dermal matrix repair, filling deeper wrinkles and stimulating multiple structural proteins including collagen, fibronectin, and hyaluronic acid.
Matrixyl® Morphomics® — A newer proprietary peptide complex. It focuses on sagging and facial contours, marketed as a solution for “morphological” signs of aging.
Matrixyl® Inside — A branding initiative used by skincare companies to certify that their products contain genuine Croda Matrixyl peptides.
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