GHRP-2 is a synthetic peptide made of five amino acids (pentapeptide) analogous to the endogenous neurotransmitter met-enkephalin.(1) Yet, the peptide appears to lack any neurotransmitter-like properties and instead appears to activate the receptors for the hormone ghrelin. Ghrelin is a naturally occurring hormone that is posited to regulate food intake.(11) Growth hormone-releasing peptide GHRP-2 may induce the secretion of growth hormone (GH) by apparently activating the ghrelin receptors on the pituitary gland, also termed as growth hormone secretagogue receptors (GHS-Rs).