Melanotan 2 Acetate (MT-II) is a synthetic cyclic heptapeptide analogue of α-MSH, supplied in lyophilized powder vials (5 mg or 10 mg) for research use only. It is characterized by high purity (>98–99%), water solubility, and activity at melanocortin receptors (MC1R, MC3R, MC4R, MC5R).

KEY FEATURES

Synthetic α-MSH analogue: Mimics natural melanocyte-stimulating hormone.

Cyclic heptapeptide: Enhanced stability via lactam bridge.

Receptor activity:

MC1R → stimulates melanin production (tanning, photoprotection).

MC3R/MC4R → appetite suppression, libido enhancement.

MC4R → erectile function modulation.

Rapid onset: Half-life ~30–60 minutes.

Research applications: Pigmentation, sexual function, appetite regulation.

TECHNICAL SPECIFICATIONS 

Molecular formula: C₅₂H₇₃N₁₅O₁₁ (acetate salt) 

Molecular weight: 1084.2 g/mol 

CAS numbers:

Melanotan II base: 121062-08-6 

Melanotan II acetate: 1036322-26-5 

Sequence: Ac-Nle-cyclo [Asp-His-D-Phe-Arg-Trp-Lys]-NH₂ (acetate salt) 

Appearance: White lyophilized powder 

Purity: ≥98–99% (HPLC/MS tested) 

Solubility: Water, bacteriostatic water

Storage:

Lyophilized: –20°C (up to 2 years), 2–8°C (up to 6 months).

Reconstituted: 2–8°C (up to 4 weeks). Avoid freeze-thaw cycles. 

AVAILABLE CONFIGURATIONS 

Vial sizes: 5 mg and 10 mg lyophilized powder 

Form: Acetate salt for improved solubility and handling 

Preparation: Reconstitution with bacteriostatic water (2 ml per vial recommended) 

Labeling: Research use only, SKU identifiers, COA provided by suppliers