Epithalon 307297-39-8
Epithalon 307297-39-8
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Epithalon (Epitalon, AEDG tetrapeptide) is a synthetic pineal peptide studied for telomerase activation, melatonin regulation, and geroprotective effects. It is supplied as a research-only compound, typically in 10 mg lyophilized vials at ≥98% purity.
KEY FEATURES
Molecular Identity: Tetrapeptide sequence Ala-Glu-Asp-Gly (AEDG).
Primary Mechanism: Activates telomerase, lengthening telomeres and potentially slowing cellular aging.
Secondary Actions:
Regulates melatonin synthesis and circadian rhythm.
Exhibits antioxidant, neuroprotective, and antimutagenic properties.
Modulates immune activity (IL-2 expression, thymocyte mitogenic activity).
Research outcomes:
Animal studies show lifespan extension.
TECHNICAL SPECIFICATIONS
Full Name: Epithalon / Epitalon / Epithalone
CAS Registry Number: 307297-39-8
Molecular Weight: 390.35 g/mol
Residues: 4 (tetrapeptide)
Sequence: H-Ala-Glu-Asp-Gly-OH
Classification: Khavinson bioregulatory peptide (pineal gland regulator)
Appearance: White to off-white lyophilized powder
Purity: ≥98% (HPLC/MS verified)
Solubility: Freely soluble in bacteriostatic water
Stability: Highly stable in lyophilized and reconstituted forms
Storage:
Lyophilized: –20 °C, protected from light
Reconstituted: 4 °C, protected from light
AVAILABLE CONFIGURATIONS :
Standard Research Format:
10 mg vial (lyophilized powder, ≥98% purity)
Supplied with batch-specific COA (HPLC, LC-MS, microbial screening)
Packaging: Tamper-evident sealed vials, research-grade labeling.
Diluent Recommendation: Bacteriostatic water for reconstitution.
Supplier Variations: Some labs may offer different vial sizes (e.g., 5 mg, 20 mg), but 10 mg ≥98% purity is the most common model.
GB
